The basis of an effective autogenous vaccine is its composition: based on the targeted selection of clearly identified and comprehensively characterized antigens. RIPAC-LABOR offers a broad spectrum of diagnostic methods for this purpose.
Ripac-Labor’s range of diagnostic services
- Pathological-anatomical examination
- Molecular biology
- MALDI-TOF MS
- Sensitivity testing
- Serological test reagents
At RIPAC-LABOR we test your samples for pathogenic infectious agents and their virulence factors, for example enterobacteria (APEC, EPEC, ESBL …) or Clostridia species including Clostridium botulinum and its neurotoxins.
MALDI-TOF mass spectrometry
RIPAC-LABOR is fast and precise when it comes to identifying microorganisms. With a trained eye, our diagnostics team can narrow down the pathogen based on morphological characteristics.
MALDI-TOF mass spectrometry provides certainty. It reveals the unique protein mass spectrum of a pathogen and compares it with the reference spectra in our extensive database. In this way, microorganisms can be clearly identified within a short time frame.
The more reference spectra the underlying database contains, the better the procedure works. As one of the first laboratories to use this technology for veterinary purposes, we can now access several tens of thousands of relevant reference spectra – and more are being added every day.
The pathogens must be present in a culture in order to be identified. For this purpose, we have developed special cultivation methods and enrichment procedures over the years. The efficient and reliable diagnostics of the RIPAC-LABOR result from the interaction of high-tech methods, specialized knowledge and many years of experience.
Serological and molecular biological tests
With our polyclonal agglutination sera we are providing targeted rapid tests for bacterial antigens which are typed by slide agglutination. By means of specific antigen-antibody reactions, ELISA can also detect subclinical infections in the blood of the animals and thus in the herd. Furthermore, we use PCR and qPCR to characterize isolates in order to determine their virulence factors such as capsule, sero or toxin antigen types.